BDBM7960 1H-1,3-benzodiazol-2-amine::2-Aminobenzimidazole::CHEMBL305513::CRA Fragment 9::Imidazole C-2 deriv. 3::JMC524454 Compound 5::US11584714, Compound 46

SMILES Nc1nc2ccccc2[nH]1

InChI Key InChIKey=JWYUFVNJZUSCSM-UHFFFAOYSA-N

Data  5 KI  8 IC50  1 Kd

PDB links: 24 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7960   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

LigandBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)Copy SMILESCopy InChI

Affinity DataKi:  1.80E+6nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLKEGGMMDBPC cidPC sidPDBPatents

In DepthDetails ArticlePubMed
Copy BDB DOI